The Arizona Cardinals defeated the Detroit Lions 25-21 as both teams are now 1-1.

The Cardinals had a +9.9 advantage in the Trench Counter, finishing with eight more first downs and limiting their penalty yards to 40 compared to 101 for the Lions. Arizona had a +4 edge in Total Rushes/Completions.

Carson Palmer went 22-for-39 for one touchdown and one interception.

Rashard Mendenhall carried 15 times for 66 yards and a touchdown that put the Cardinals out ahead in the final two minutes of the fourth quarter.

Matthew Stafford went 24-for-36 for 278 yards and two touchdowns in the first quarter to Calvin Johnson. Johnson finished with 116 yards receiving.

The Denver Broncos defeated the Baltimore Ravens by a final score of 49-27 as Peyton Manning threw for seven touchdowns and 462 yards.

The Broncos had a +9.6 advantage in The Trench Counter, nearly doubling up the Ravens in terms of yards per pass (10.6 to 5.4). Denver and Baltimore each gained 2.8 yards per carry, 24 first downs and two turnovers. The Ravens had a +5 edge in Total Rushes/Completions.

Manning struggled in the first half to connect to anyone other than Julius Thomas and Wes Welker. Julius Thomas finished with two touchdowns and 110 yards, while Demaryius Thomas had an excellent second half with two touchdowns and 161 yards.

Joe Flacco lost Jacoby Jones in the first half and didn't look particularly comfortable targeting Dallas Clark and Brandon Stokley more than 10 times apiece. Flacco finished the game 34-for-62 for 362 yards, two touchdowns and two interceptions. 

Ray Rice carried just 12 times for 36 yards and a goalline touchdown off Welker's fumble on a punt.